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PhD Candidate (f/m) in Cancer Immunotherapy

Deutsches Krebsforschungszentrum / German Cancer Research Center (DKFZ). 55131 Mainz, 17.05.2017

The German Cancer Research Center is committed to increase the percentage of female scientists and encourages female applicants to apply. Among candidates of equal aptitude and qualifications, a person with disabilities will be given preference.
To apply for a position please use our online application portal (www.dkfz.de).
We ask for your understanding that we cannot return application documents that are sent to us by post (Deutsches Krebs­for­schungs­zentrum, Personal­abteilung, Im Neuenheimer Feld 280, 69120 Heidelberg) and that we do not accept applications submitted via email. We apologize for any inconvenience this may cause.
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The German Cancer Research Center (DKFZ), the largest biomedical research institute in Germany operates a comprehensive program in the field of cancer research. Together with university partners at seven renowned partner sites, we have established the German Cancer Consortium (DKTK).

For the partner site of DKTK Frankfurt / Mainz the German Cancer Research Center is seeking for September / October 2017 a

PhD Candidate
in Cancer Immunotherapy

(Ref-No. 148/2017)

Description:
The University Medical Center (UCT) Mainz of the Johannes Gutenberg University Mainz is ranked as a leading research institution of Germany having a strong cancer immunology program. The UCT Mainz is one of the seven translation centers, together with the partner city of Frankfurt am Main, which, together with the German Cancer Research Center (DKFZ) in Heidelberg, forms the alliance of the German Consortium for Translational Cancer Research (DKTK).
The newly established DKTK / DKFZ laboratory research group of Dr. Guezguez at the Department of Hematology / Oncology / Pneumology of UCT Mainz is seeking highly qualified and talented students who would like to undertake a PhD fellowship in cancer immunotherapy.
Our research program is focused on dissecting the molecular and cellular regulation derived from specialized bone marrow microenvironment called “niche” that underlies the self-renewal / survival of normal hematopoietic stem cells and their malignant leukemia stem cell counterparts. In doing so we aim to identify the processes that when dysregulated lead to leukemic transformation and relapse and therefore represent critical therapeutic targets for the clinic. (Guezguez et al., Stem Cells 2010; Guezguez et al., Cell Stem Cell 2013; Guezguez et al., Cancer Cell 2016).
Your profile:
Highly motivated candidates with an outstanding university degree in biology, biochemistry or related fields that have an interest in hematological malignancies with a particular emphasis in tumor microenvironment and cancer immunotherapy. Strong background in stem cell biology, oncology or immunology is essential. Experience in primary cell culture techniques, complex multicolor flow cytometry, immunohistochemistry, and in mouse experimentation would be beneficial. Excellent communication and writing skills in English are required.
If you are interested in joining this ambitious team in an exciting field of stem cell and cancer research, then please send the complete application in English (one PDF file) including a motivation letter, CV, a brief summary of previous research experience and two references.
The position is limited to 3 years.
The Translation Center is located at the University
Medical Center (UCT) in Mainz.


For further information please contact
Dr. Borhane Guezguez, phone +49 6131 179785.
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