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Post-doc (f/m) Regulation of HSCs by niche cells

Universitätsklinikum Carl Gustav Carus Dresden. Dresden, 11.04.2017

The group Regeneration in Hematopoiesis in the Institute for Immunology at the Technical University Dresden focuses on fundamental research on hematopoietic regeneration and stem cells in the embryo and adult mouse.
Available in 2017 is the following position:

Post-doc (f/m): Regulation of
HSCs by niche cells.

We are seeking a highly motivated Post-doc, who will contribute to the analysis of the regulation of hematopoietic stem cells (HSCs) by niche cells, but also determine effects of hematopoietic cells on niche cell responses to stress. The Post-doc will perform state-of-the-art transplantation experiments, using unique mouse models exclusively available in our working group, and determine the quality of the interaction between distinct niche cell types and HSCs and early hematopoietic progenitor cells. In addition, the scientists will perform a multiplexed screen on novel genes involved in functional regulation of HSCs as determined by bioinformatics integration of next generation sequencing data and a newly generated INTERACTOME database. Finally, novel targets will be assessed for their functional relevance in vitro and in vivo.
Your profile:
The applicant should have experience in molecular biology (cloning, PCR), flow cytometry and animal handling and experimentation (mouse). Experience in histological techniques is also beneficial. The operating language of the group is English.
For further information see
Severely disabled persons are explicitly encouraged to apply.
We kindly ask you to apply preferably via our online form to make the selection process faster and more effective. Of course, we also consider your written application without any disadvantages. Please send your electronic application in english as a pdf-file (only as one PDF document, max 8 MB), latest by May 05, 2017 to; registration number IMU0917703.

Bewerbungsschluss: 05.05.2017