Head of Proteomics Research Platform

The Max Planck Unit for the Science of Pathogens headed by its director Prof. Emmanuelle Charpentier is seeking a full time scientist position to head a Research Platform for Proteomics.

The Max Planck Unit for the Science of Pathogens is an international research institute currently being established, whose research focuses on basic biological principles in bacterial pathogens (https://www.emmanuelle-charpentier-lab.org). We are particular interested in genetic and biochemical mechanisms of regulation by RNAs and proteins in bacterial pathogens causing diseases in humans, and in viruses of these pathogens. The overall aims of the Unit`s research are to gain a better understanding of the molecular and cellular mechanisms that control and regulate bacterial infectious processes.

We are seeking a highly motivated and talented scientist with excellent skills and knowledge in mass spectrometry to establish and direct a state-of-the-art Proteomics Research Platform, including personnel. The successful candidate will be expected to develop, innovate and implement new advances in technology and bioinformatics relevant to proteomics to support and propel research forward at our Unit. The successful candidate’s tasks include general management of the research platform, instrument maintenance, routine analyses and method development, as well as all data acquisition and interpretation. The Unit also hosts a Bioinformatics Research Platform that will provide support for data analysis. In addition, resources will be available to follow independent research projects.

The successful applicant should have experience in:

• Handling LC-MS/MS
• Global proteome profiling by Data-Dependent and Data-Independent Acquisition (DIA) mass-spectrometry
• Post-translational modification (phosphorylation, oxidation, lysine-acetylation) profiling
• Relative quantification of proteins and proteomes by stable isotope labeling/proteome-wide quantification techniques, including label-free, SILAC, stable isotope dimethyl labeling, iTRAQ and/ or TMT
• In vivo proteomics of bacterial infections
• Structural proteomics (cross-linking)

The successful candidate will join an international and collaborative team in an outstanding and competitive scientific environment. We are seeking highly qualified scientists with an excellent research track record. The successful candidate is expected to set up and maintain the scientific and technical expertise of the research platform, support research at the highest standards, oversee the work of younger scientists (PhD, master and undergraduate students), and contribute actively to collaborative and complementary research across the Unit.

The candidate’s qualification should include:

• PhD in Biochemistry, Chemistry, Genetics, Immunology, Microbiology and/or Molecular Biology
• Hands-on experience with LC-MS/MS, quantification methods and bioinformatics
• A proven record of successful publications in highly respected international scientific journals
• A successful post-doctoral experience
• Fluent in English language
• Experience working abroad is considered as an advantage
• Friendly disposition, confident and responsible work ethics
• Working independently and as part of an international team
• Self-motivated and enthusiastic to work in a competitive, dynamic, stimulating and interacting international scientific environment focusing on basic biological research

The position is initially for five years with the possibility of becoming a permanent position after positive evaluation. The payment level is based on the German state public service salary scale (up to E15, TVöD-Bund) according to the training, qualifications and professional experience. The benefits correspond to the regulations of the public service. The position is available at the earliest possible date. The Max Planck Society is committed to employing more handicapped individuals and especially encourages them to apply. Furthermore, the Max Planck Society seeks to increase the number of women in those areas where they are underrepresented and therefore explicitly encouraged women to apply.

Applications will be accepted exclusively via our online application portal. If you are interested, please follow the link https://recruitingapp-5133.de.umantis.com/Vacancies/381/Application/New/2?lang=eng and upload your full application in English by September 30th, 2018:

Max Planck Unit for the Science of Pathogens
Department of Human Resources