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PhD position (f/m/d) Translational Neurooncology
Forschungszentrum Jülich GmbH
As a member of the Helmholtz Association, Forschungszentrum Jülich makes an effective contribution to solving major challenges facing society in the
fields of information, energy, and bioeconomy. It focuses on varied tasks in the area of research management and utilizes large, often unique, scientific
infrastructure. Come and work with around 6,100 colleagues across a range of topics and disciplines at one of Europe's largest research centres.
The Institute of Complex Systems (ICS-7), "Biomechanics" conducts fundamental research focused on the biomechanics of mammalian cells and their mechanical interaction
with the environment. Modern methods of cell biophysics and cell biology complemented by biomimetic model systems are used.
The Institute of Neuroscience and Medicine (INM-3), "Cognitive Neuroscience" uses behavioural, pharmacological, and neuromodulatory methods to investigate the neural
mechanisms underlying cognitive (dys-)function in healthy subjects and patients suffering from neurological disorders. Functional imaging (PET, MRI) and electrophysiological
methods (EEG, TMS, tDCS) are combined with computational approaches to achieve a better understanding of i) the development of normal brain functions during ageing, ii)
disease-induced dysfunction, and iii) cerebral plasticity and recovery of function. Results help to decode how the human brain enables higher cognition and to develop novel therapeutic approaches.
We are offering a
PhD position - Translational Neurooncology
In collaboration between researchers at ICS-7 and INM-3, the potential of selectively expressed RNA (seRNA) molecules to treat experimental glioma is investigated.
In order to facilitate the translation of this therapeutic approach from bench to bedside, non-invasive in vivo imaging techniques (MRI, PET) are combined with
histological read-outs. You will investigate how intracranial glioma in nude mice are affected by local treatment with seRNA under the supervision of PD. Dr.
Bernd Hoffmann (ICS-7) and Prof. Maria Adele Rueger (INM-3).
Your tasks in detail:
stereotactic injections into the brain of nude mice
non-invasive MRI and PET-imaging of experimental animals
presentation and publication of the results
interaction with team members and collaborators from University Hospital Köln as well as other institutes with the FZ Jülich and industrial partners
university degree (Diploma / Master) in veterinary medicine, neuroscience, biology or a related field
animal handling skills, preferably experience with anesthesia and surgery in rodents
laboratory animal science course according to the Federation of European Laboratory Animal Science (FELASA), category B, or equivalent
good command of German or English
mobility and willingness to conduct experiments both at FZ Jülich and University Hospital Köln
a stimulating, collaborative, and international research environment
excellent working conditions
continuous scientific mentoring by your scientific advisors
doctoral degree conferred by University of Köln (Medical Faculty) or University of Bonn (Faculty of Sciences), depending on previous academic degree
usually a contract for the duration of 3 years
further development of your personal strengths, e.g. via a comprehensive further training programme
pay in line with 65 % of pay group 13 of the Collective Agreement for the Public Service (TVöD-Bund)
Applications are welcome in English or German.
Forschungszentrum Jülich aims to employ more women in this area and therefore particularly welcomes applications from women.
We also welcome applications from disabled persons.
We look forward to receiving your application, preferably via our
online recruitment system on our career site, quoting the reference number 2019D-186.
Questions about the vacancy?
Contact us by mentioning the reference
number 2019D-186: firstname.lastname@example.org
Please note that for technical reasons we cannot accept applications via e-mail.