With more than 38,000 students and more than 250 fields of study, the Friedrich-Alexander-University Erlangen-Nürnberg (FAU) is the second largest state university in Bavaria and belongs to the top 10 largest universities in Germany. The research output of the FAU Faculty of Medicine ranks among the top 6 in Germany. At the Institute of Cellular and Molecular Physiology, we offer a postdoctoral (m/f/d) and a PhD (m/f/d) position in the scope of externally funded projects (e.g. DFG) starting October 1, 2022 or later. We are looking for highly motivated individuals passionate about cardiac research.
We investigate the causes and consequences of pathophysiological changes in heart failure and arrhythmias (excitation-contraction coupling, fibrosis, electrophysiology). Alterations in the transverse tubular system of cardiac myocytes contribute significantly to arrhythmogenesis and reduced contractility in heart failure. The underlying causes and signaling pathways, however, remain largely unclear. A main goal of this project is to elucidate the molecular mechanisms leading to t-system loss in isolated cardiomyocytes and intact cardiac tissue.
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