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We want to break tolerance mechanisms in Anopheles, the mosquito transmitting the malaria parasite (Plasmodium spp). After infection, the parasite manipulates the immune response and induces tolerance mechanisms in the mosquito.
We will analyze and model metabolism, signaling and regulatory networks of infected and non infected cells of the mosquito using gene expression and genomic data. We employ machine learning methods, statistics, network analysis methods, own developments determining infection specific regulation to identify specific drug targets for biocidal development. Collaboration partners in Nigeria will support these analyzes and a partner in Mali will experimentally validate promising candidates applying Crispr/Cas technology.
If you are interested in immunology, in systematically detecting functional patterns in networks or machine learning, are experienced in the analysis of high throughput data, are a good team player, have organizational talent and hold a PhD degree in bioinformatics, biology or related subjects, we are looking forward to your application.
Jena University Hospital:
Being the largest employer in the region, our around 5,000 employees working in 26 departments and clinics provide ambulatory care for around 280,000 patients and inpatient treatment for more than 55,000 patients each year. In addition, 2,300 students of medicine and dentistry are trained, and in 25 institutes, scientists from more than 25 nations do research to advance medicine.
Employees at Jena University Hospital can benefit from a wide range of offers that encourage individual health promotion at work.
We are a team of a couple of phd-students, two postdocs, varying undergraduates and the group leader. We are offering a postdoctoral fellowship position for 3 year (TVL E-13) starting as soon as possible, an extension is planned.
We prefer online applications. Please apply for this job via our online application tool on www.uniklinikum-jena.de/Karriere or send your documents (letter of motivation, CV, certificates, preferably within one pdf), indicating reference number DM43/2017 to email@example.com
In case of equal qualification, persons with disabilities will be given priority.
Prof. Dr. Rainer König, Jena University Hospital, Germany
Deadline of application: 30 November 2017.